CHEMOENZYMATIC SYNTHESIS OF BICYCLIC GAMMA-LACTAMS USING CLAVAMINIC ACID SYNTHASE

Authors
BALDWIN JE ADLINGTON RM BRYANS JS LLOYD MD SEWELL TJ SCHOFIELD CJ BAGGALEY KH CASSELS R
Citation
Je. Baldwin et al., CHEMOENZYMATIC SYNTHESIS OF BICYCLIC GAMMA-LACTAMS USING CLAVAMINIC ACID SYNTHASE, Tetrahedron, 53(20), 1997, pp. 7011-7020
Citations number
44
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
20
Year of publication
1997
Pages
7011 - 7020
Database
ISI
SICI code
0040-4020(1997)53:20<7011:CSOBGU>2.0.ZU;2-C
Abstract
Incubation of the gamma-lactam analogue of proclavaminic acid, eo-5-am ino-3-hydroxy-2-(1'-aza-2'-oxocyclopentyl)- pentanoic acid, led to pro duction of two bicyclic gamma-lactam products. (C) 1997 Elsevier Scien ce Ltd.