Mandibulofacial dysostosis - Variability in facial morphology and growth: A long-term profile roentgenographic and roentgen stereometric analysis of three patients

Objective: To monitor and compare facial morphology and growth in three ind ividuals with variable expression of mandibulofacial dysostosis (MFD) in te rms of changes in the skeletal profile and in terms of growth in the circum -maxillary sutures and temporomandibular joints (TMJs), Design: Retrospective conventional profile roentgenography (mean age 9 to 1 8 years) and prospective roentgen stereometric analysis (RSA) (mean age 7 t o 17 years). Setting: Center for Craniofacial Anomalies and Department of Plastic and Re constructive Surgery, Malmo University Hospital, Sweden. Patients: The first three MFD patients seen by one of the authors (B.R,), I nterventions: Surgery was performed at the Department of Plastic and Recons tructive Surgery. Implants were inserted at surgery under general anesthesi a. Roentgen examinations were performed in connection with continued clinic al evaluations and treatment. Main Outcome Measures: All profile roentgenograms were traced and measured by one of the authors (K.-V.S.) using a conventional point-based analysis. Results: The more afflicted patient showed a greater total difference in pr ofile morphology and growth from the norm and more pronounced effects of ar ticular growth restriction. Little change in the skeletal profile was assoc iated with considerable displacement of the jaws. Conclusions: The variability in MFD expression and surgical procedures in o ur patients is reflected less in the skeletal profile morphology and growth and more in the displacement of the jaws.