This article is an extensive review of the psychological literature on clef
t lip and palate and other craniofacial anomalies. Issues of parental accep
tance, social competence, self-concept, emotional adjustment, and cognitive
functioning are examined. Cumulative research suggests that many children
with craniofacial conditions develop in a typical manner and do not experie
nce psychological problems. However, a significant number of children (30%
to 40% in most studies) experience difficulties with internalizing and/or e
xternalizing problems, learning disorders, and social competence. A multifa
ctorial model for examining the domains that are related to both psychologi
cal risk and protection is recommended. The need for multicenter studies th
at are prospective and clinically relevant is emphasized.