Transfer RNA biogenesis: A visa to leave the nucleus?

Authors
Citation
G. Simos et E. Hurt, Transfer RNA biogenesis: A visa to leave the nucleus?, CURR BIOL, 9(7), 1999, pp. R238-R241
Citations number
12
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
9
Issue
7
Year of publication
1999
Pages
R238 - R241
Database
ISI
SICI code
0960-9822(19990408)9:7<R238:TRBAVT>2.0.ZU;2-N
Abstract
Only correctly folded and mature tRNAs can leave the nucleus and enter the cytoplasm, Surprisingly, tRNA-aminoacylation has been found to occur, not o nly in the cytosol, but also inside the nucleus, where it may act as an add itional proofreading step and facilitate the export of 'ready-to-function' aminoacyl-tRNAs.