STEREOSELECTIVE ENZYMATIC GALACTOSYLATION OF C-GLUCOSIDES

Authors
PANZA L CHIAPPINI PL RUSSO G MONTI D RIVA S
Citation
L. Panza et al., STEREOSELECTIVE ENZYMATIC GALACTOSYLATION OF C-GLUCOSIDES, Journal of the Chemical Society. Perkin transactions. I, (9), 1997, pp. 1255-1256
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
9
Year of publication
1997
Pages
1255 - 1256
Database
ISI
SICI code
0300-922X(1997):9<1255:SEGOC>2.0.ZU;2-J
Abstract
The enzyme beta-1,4-galactosyl transferase from bovine colostrum (GalT ) is able stereoselectively to galactosylate C-glucosides (i.e. 1 and 4), precursors of stable glycoconjugate analogues, and a systematic in vestigation of the structural modifications at C-1 and/or C-5 of the g lycosides that can be accepted by this enzyme has been undertaken, add ing information to the currently accepted model of substrate binding i nto the GalT active site.