Left ventricular (LV) mural thrombus is a well recognized complication of a
cute myocardial infarction. In survivors of infarction, its incidence is in
fluenced by the location, and magnitude of infarction: it occurs often in p
atients with large anterior Q wave infarctions, particularly in the presenc
e of LV apical akinesis or dyskinesis. Although radionuclide imaging with i
ndium-111-labeled platelets, computed tomography, and magnetic resonance im
aging may be used to identify LV mural thrombus, two-dimensional echocardio
graphy is the technique of choice for assessing its presence, shape, and si
ze, and recent technical advances in, echocardiographic methodology, such a
s high-frequency, short-focal-length transducers, have improved the echocar
diographic assessment of LV mural thrombus. In the patient in whom a mural
thrombus is identified, acute and chronic anticoagulation (with heparin and
warfarin, respectively) is indicated: first, to prevent further thrombus f
ormation and, second, to reduce the incidence of systemic embolization.