This essay reports on a historical study of the evolution of seven major hi
gh-tech industries. The aim was to identify key factors leading to the emer
gence of industrial leadership. A few lessons have come to the fore. First,
firms that become dominant on world markets first became strong in their h
ome market. Second, important sources of comparative advantage often reside
in sectoral support systems e.g. a university especially strong in organic
chemistry. As to the debate about industrial policy, history shows many in
stances that support the case for targeted support. On the other hand, we s
hould not ignore that the success of industrial policy depends to a large e
xtent on the interaction between firms and the relevant government agencies
.