Imaging technologies for assessing neuroprotection in glaucomatous optic neuropathy

The confocal scanning laser ophthalmoscope and the scanning laser polarimet er are two new imaging devices that may be beneficial in the diagnosis and monitoring of glaucoma patients. For each of these instruments, the authors describe benefits and limitations with regard to imaging mechanisms, sensi tivity, and clinical applications. In comparison with currently used tests for glaucoma, these instruments provide quantitative assessment of the opti c disc and RNFL at the clinic visit, with reduced need for pupil dilation a nd clear media. They also show promise for improving the ability to monitor progression of glaucomatous optic neuropathy and might allow better assess ment of the efficacy of a neuroprotective agent. (Eur J Ophthalmol 1999; 9: S40-S43).