An efficient route to formyldeuteroporphyrins and their Wittig reaction

Authors
Ando, A Yamazaki, M Komura, M Sano, Y Hattori, N Omote, M Kumadaki, I
Citation
A. Ando et al., An efficient route to formyldeuteroporphyrins and their Wittig reaction, HETEROCYCLE, 50(2), 1999, pp. 913-918
Citations number
7
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
50
Issue
2
Year of publication
1999
Pages
913 - 918
Database
ISI
SICI code
0385-5414(19990401)50:2<913:AERTFA>2.0.ZU;2-I
Abstract
Copper complex of deuteroporphyrin dimethyl ester (2) was formylated with t rimethyl orthoformate in the presence of tin(IV) chloride, followed by deme tallation with H2SO4-CF3COOH and separation by column chromatography to giv e 3- (5) and 8-formyl compounds (6) in 46 and 47% yields, respectively. The Wittig reaction of these formylporphyrins gave highly functionallized deri vatives of porphyrin.