Pr. Kumar et Ms. Reddy, Synthesis of 2,3-dihydro-2-substituted benzo [g] quinazolin-4 (1H) ones and their heteroaromatic analogues, I J HET CHE, 8(3), 1999, pp. 201-204
Condensation of 3-amino-2-naphthamide (I) with aldehydes in equimolar propo
rtions in hot acetic acid results in 2,3-dihydro-2-substituted benzo [g] qu
inazolin-4 (1H)-ones (II). Dehydrogenation of II using potassium permangana
te in acetone leads to 2-substituted benzo [g] quinazolin-4 (3H)-ones (IV).
All the compounds have been characterized by elemental analyses, IR, mass
and H-1 NMR spectral data.