Influenza virus overcomes apoptosis by rapid multiplication

Authors
Kurokawa, M Koyama, AH Yasuoka, S Adachi, A
Citation
M. Kurokawa et al., Influenza virus overcomes apoptosis by rapid multiplication, INT J MOL M, 3(5), 1999, pp. 527-530
Citations number
21
Categorie Soggetti
Medical Research General Topics
Journal title
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
ISSN journal
11073756 → ACNP
Volume
3
Issue
5
Year of publication
1999
Pages
527 - 530
Database
ISI
SICI code
1107-3756(199905)3:5<527:IVOABR>2.0.ZU;2-6
Abstract
The kinetics of apoptotic fragmentation of the chromosomal DNA was determin ed in the influenza virus-infected MDCK, HeLa and KB cells, respectively. C omparison of these kinetics with the kinetics of virus multiplication revea led that the multiplication of influenza virus was observed only when apopt osis was induced after the production of progeny virus in the infected cell s. The extent of apoptotic response was reversely correlated with the permi ssiveness of the cells.