D. Chappard et al., The early remodeling phases around titanium implants: A histomorphometric assessment of bone quality in a 3- and 6-month study in sheep, INT J O M I, 14(2), 1999, pp. 189-196
Citations number
31
Categorie Soggetti
Dentistry/Oral Surgery & Medicine
Journal title
INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
The purpose of this study was to evaluate the quality of the bone matrix ar
ound commercially pure titanium implants at 3 and 6 months postplacement in
sheep. Implants were placed in the corticotrabecular areas of both femurs
in 6 animals. Each animal received 4 Euroteknika implants in the right femu
r and 4 Nobel Biocare implants in the left femur. Bone blocks containing th
e implants were studied undecalcified after being embedded in methylmethacr
ylate. Sections were stained with toluidine blue and basic fuchsin. The amo
unt of bone around the implants, the contact interface between the implant
and bone, and the mineral apposition rates were measured. The fractional am
ount of woven bone could be quantified because of its high glycosaminoglyca
n content. No differences could be observed between the 2 types of implants
. Total bone volume did not increase around both types of implants between
3 and 6 months, indicating that ankylosis was rapidly achieved. In contrast
, in the area in contact with the implant, the bone-titanium interface dras
tically increased and the mineral apposition rate decreased. The fractional
volume of woven bone around implants was considerably reduced alter 6 mont
hs. Bone quality around implants was improved at 6 months (volume of woven
bone near zero), and true osteonic structures were observed in close contac
t with titanium. The remodeling process appeared to improve bone quality an
d increase the bone-titanium interface around implants, while the net bone
quantity necessary to immobilize implants was achieved rapidly and remained
unchanged.