We aimed to investigate the prevalence of ulcerative sexually transmissible
diseases (STDs) and hepatitis in crack users. We interviewed 435 crack use
rs on site in crack houses in Houston, Texas and took blood for laboratory
analysis. There was evidence of syphilis infection in 13%, herpes simplex v
irus-2 (HSV-2) in 61%, HIV in 12%, hepatitis B in 52%, and hepatitis C in 4
1% of cases. On DSM-III-R criteria, 12% were crack abusers and 84% crack de
pendent: over half reported previous treatment. Forty per cent reported als
o injecting. Sexual behaviour indicated a mean of 2.4 partners in the past
month for men, 3.7 for women. Sexual behaviour was largely vaginal, althoug
h women also reported more than twice the level of oral sex of men. Signifi
cant multivariate predictors for HIV and hepatitis B and C were previous re
ported STD and injecting drug use (including sharing needles), while female
gender for syphilis and HSV-2 and additionally condom use for HSV-2 were s
ignificant risks. These data confirm high rates of STDs in a crack house po
pulation as inferred from previous clinic-based and community studies, and
the link between STDs, injecting and HIV. The high rates of STDs found shou
ld lead to considering STDs and substance abuse to be dual diagnoses in cra
ck users and the integration of STD diagnosis and treatment into crack outr
each and treatment programmes.