The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1

Authors
Casal, M Paiva, S Andrade, RP Gancedo, C Leao, C
Citation
M. Casal et al., The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1, J BACT, 181(8), 1999, pp. 2620-2623
Citations number
22
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
181
Issue
8
Year of publication
1999
Pages
2620 - 2623
Database
ISI
SICI code
0021-9193(199904)181:8<2620:TLSOSC>2.0.ZU;2-H
Abstract
A mutant of Saccharomyces cerevisiae deficient in the lactate-proton sympor t was isolated, Transformation of the mutant with a yeast genomic library a llowed the isolation of the gene JEN1 that restored lactate transport. Disr uption of JEN1 abolished uptake of lactate. The results indicate that, unde r the experimental conditions tested, no other monocarboxylate permease is able to efficiently transport lactate in S. cerevisiae.