Characterization of amine functionalized stationary phases using linear solvation energy relationships

In a continuing effort to develop quantitative structure-solubility relatio nships, this work describes the characterization of four amine functionaliz ed stationary phases: Quadrol, tetraethylene pentamine, phenyldiethanolamin e succinate, and triethanolamine. Solubility properties of these materials were examined using linear solvation energy relationship of the following f orm: log K = c + r(1)R(2) + s(1) pi(2)(H) + a(1)Sigma alpha(2)(H) + b(1)Sigma be ta(2)(H) + l(1) log L-16 in which the coefficients (subscript 1) represent the ability of the statio nary phase to engage in specific interactions. These coefficient values wer e correlated with the fraction of amine functionalities in the phase, and w ere quantitatively compared with literature values for similar nitrogen con taining (amide) stationary phases. (C) 1999 Published by Elsevier Science B .V. All rights reserved.