M. Al-yamany et al., Isolated oculomotor nerve palsy: an unusual presentation of glioblastoma multiforme. Case report and review of the literature, J NEURO-ONC, 41(1), 1999, pp. 77-80
The authors present a case of a very unusual clinical presentation of an in
tra-axial supratentorial glioblastoma multiforme (GBM) in a 63 year old dia
betic female patient presenting with a three week history of left progressi
ve complete oculomotor nerve palsy. CT scan and magnetic resonance imaging
of the head revealed a left intra-axial mesial temporal glioblastoma multif
orme. Operative resection and microscopic examination of a tissue specimen
confirmed the diagnosis. The nature of the tumor, the pattern of spread and
the postulated mechanisms of such a presentation are discussed. The author
s suggest including the diagnosis of GBM in the differential diagnosis of p
atients with isolated complete oculomotor nerve palsy at the appropriate ag
e group.