Plasma cell mucositis: a review and case report

The simultaneous involvement of the mucous membranes of the oral cavity and upper aerodigestive tract by lesions characterised clinically by an intens ely erythematous, lobulated surface and histologically by a dense connectiv e tissue infiltrate composed of non-neoplastic plasma cells may be called p lasma cell mucositis. We present a review of the literature, consisting of 14 cases, outlining the multifocal site distribution, chronicity and system ic background that distinguish this entity and report a single case with co nfirmation of the polyclonal nature of the plasma cell infiltrate using gen e rearrangement studies.