Cb. Del Mar et Pp. Glasziou, Should we now hold back from initially prescribing antibiotics for acute otitis media?, J PAEDIAT C, 35(1), 1999, pp. 9-10
The research literature provides surprisingly little evidence of benefit fo
r initially treating acute otitis media in children with antibiotics. We sh
ow how to calculate the amount of benefit and harm from the evidence, and h
ow this might be applied to change management practice.