This study analyzes the reciprocal relationships between place and labor ma
rket segmentation by focusing on occupational sex segregation in Minneapoli
s-St. Paul. On the one hand employment maps confirm that segmentation produ
ces distinctive places: The slotting of women and men into different lines
of work inscribes fine-grained spatial labor submarkets in different parts
of the metropolis. On the other hand, logistic regression analyses confirm
that place matters in segmentation processes: Workplace location significan
tly influences the likelihood of occupational sex segregation even after co
ntrolling for human capital and residential location factors. Occupational
desegregation has advanced most rapidly with the emergence of new opportuni
ties in suburban growth corridors. Continued suburban expansion and industr
ial restructuring promise increasing complexity of spatial mismatch and spa
tial segmentation and demand that employment policy incorporate issues of s
pace, place, and scale.