Parathyroid hormone related protein and carcinoma of the penis: Paraneoplastic hypercalcemia

Malignancy associated hypercalcemia occurs in several genitourinary tumors and is a common life threatening metabolic disorder.(1-3) In these patients an elevated parathyroid hormone like activity can be occasionally demonstr ated, indicating a paraneoplastic effect, Recently, evidence of the associa tion of hypercalcemia and squamous cell carcinoma of the penis has emerged. (4) We report a case of advanced penile carcinoma with hypercalcemia and si multaneously elevated parathyroid hormone related protein levels.