Effect of the RNase from Bacillus intermedius on the Trophic Organization of the Mitotic cycle of Candida utilis

The effect of the RNase from Bacillus intermedius on the growth and trophic cycle of Candida utilis was studied. RNase at concentrations of 0.001-0.01 mu g/ml stimulated yeast growth by 30-40% as compared to the control, redu ced the mitotic cycle of the yeast by shortening its G1 phase, and decrease d the number of exotrophic cells in the G1 phase to a minimum. It is sugges ted that RNase is involved in the regulation of the transition of cells fro m the exo- to endotrophic state.