WIDESPREAD CUTANEOUS NECROSIS AND ANTIPHOSPHOLIPID ANTIBODIES - 2 EPISODES RELATED TO SURGICAL MANIPULATION AND URINARY-TRACT INFECTION

Authors
DELCASTILLO LF SORIA C SCHOENDORFF C GARCIA CG DIEZCABALLERO N ALEN AR SAEZ AI URRUTIA S ALMAGRO DG
Citation
Lf. Delcastillo et al., WIDESPREAD CUTANEOUS NECROSIS AND ANTIPHOSPHOLIPID ANTIBODIES - 2 EPISODES RELATED TO SURGICAL MANIPULATION AND URINARY-TRACT INFECTION, Journal of the American Academy of Dermatology, 36(5), 1997, pp. 872-875
Citations number
15
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Journal of the American Academy of Dermatology → ACNP
ISSN journal
01909622
Volume
36
Issue
5
Year of publication
1997
Part
2
Supplement
S
Pages
872 - 875
Database
ISI
SICI code
0190-9622(1997)36:5<872:WCNAAA>2.0.ZU;2-1
Abstract
Widespread cutaneous necrosis (WCN) associated with antiphospholipid a ntibodies is rare. Its mechanisms have yet to be elucidated, and there are no well-established guidelines for its management. We describe a woman who had two episodes of WCN related to surgical manipulation for urinary tract obstruction and urinary tract infection. Lupus anticoag ulant was always positive. In the second episode anticardiolipin antib odies were elevated, and protein C levels were temporarily decreased. We found only ten previously reported cases of WCN associated with ant iphospholipid antibodies, none of which were related to surgical manip ulation.