Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barre syndrome

Authors
Mori, M Kuwabara, S Miyake, M Dezawa, M Adachi-Usami, E Kuroki, H Noda, M Hattori, T
Citation
M. Mori et al., Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barre syndrome, NEUROLOGY, 52(6), 1999, pp. 1282-1284
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
52
Issue
6
Year of publication
1999
Pages
1282 - 1284
Database
ISI
SICI code
0028-3878(19990412)52:6<1282:HIHAGG>2.0.ZU;2-P
Abstract
The authors report a patient with an axonal Guillain-Barre syndrome (acute motor axonal neuropathy) associated with anti-GM1 antibody after Haemophilu s influenzae infection. The result of ELISA inhibition studies and cytochem ical staining with cholera toxin suggest the presence of a GM1-like structu re on the surface of H. influenzae isolated from the patient. A particular strain of H. influenzae may have a GM1-like structure and may elicit an axo nal Guillain-Barre syndrome.