A case of granuloma inguinale (GI) presenting as a lateral neck mass in a I
-month-old, HIV-positive infant is described. The histological features of
the mass were typical of GI, with numerous macrophages containing intracell
ular organisms with a "closed-safety-pin" appearance. This is a rare occurr
ence, and the mode of transmission of infection is discussed. An awareness
of GI in infants by both clinicians and pathologists is important to preven
t morbidity and allow for prompt institution of appropriate treatment.