Extrahepatic biliary atresia associated with trisomy 18

A case of extrahepatic biliary atresia (EBA) associated with trisomy 18 is presented. A 1-month-old boy was suspected to have Alagille syndrome with o bstructive jaundice, a systolic heart murmur, growth retardation, and a sma ll, pointed chin. However, surgery and chromosomal analysis revealed EBA as sociated with trisomy 18. Chromosomal examination must be performed in pati ents with jaundice and congenital anomalies. It is possible that EBA in tri somy 18 syndrome is due to a chromosomal disorder.