Pd. Steinbach et al., OPHTHALMIC FLUOROMETHOLONE-GENTAMICIN VERSUS OPHTHALMIC BETAMETHASONE-GENTAMICIN FOLLOWING CATARACT-SURGERY, Ocular immunology and inflammation, 5(1), 1997, pp. 51-54
A prospective, randomised, investigator-masked, parallel-group study w
as performed to compare fluorometholone-gentamicin eye drops and ointm
ent with betamethasone-gentamicin eyedrops and ointment in the control
of ocular inflammation after cataract surgery. Seventy patients (35 i
n each treatment group) of both sexes undergoing cataract-lens implant
surgery for visually disabling cataract were enrolled in the study. T
he demographic and baseline parameters on day I, the day after surgery
, were similar in the two study groups. After treatment, on day 3 and
day 6 post-operatively, the reduction in cells in the anterior chamber
and conjunctival hyperaemia were similar in the two study groups. Bot
h treatments were equally well-tolerated. Ophthalmic fluorometholone-g
entamicin was as effective as ophthalmic betamethasone-gentamicin in t
he control of ocular inflammation after cataract surgery.