Diagnosis of epileptic seizures is often based on temporal lobe epilep
tiform abnormalities appearing on interictal EEG, when reported ictal
semiologies are consistent with temporal lobe seizures. It is unclear
how often such patients have non-epileptic seizures. We studied 145 pa
tients who had temporal interictal EEG spikes and reported ictal semio
logy characteristic of temporal lobe seizures, with long-term EEG-vide
o-monitoring (LTM) for presurgical evaluation of medically refractory
seizures. Nonepileptic seizures were unexpectedly recorded in 12 of th
ese patients (8%). Outcomes after LTM in patients who had both epilept
ic seizures and nonepileptic seizures demonstrated that the epileptic
seizures usually were controlled with medications. Our observations su
pport LTM as useful in diagnosis of non-epileptic seizures in this gro
up of patients. We suggest that ictal recordings always should be perf
ormed before epilepsy surgery, in part to avoid unintentional surgical
treatment of nonepileptic seizures.