An approach towards enantiomerically pure taxoidic A,B-ring fragments

Authors
Wenz, M Grossbach, D Beitzel, M Blechert, S
Citation
M. Wenz et al., An approach towards enantiomerically pure taxoidic A,B-ring fragments, SYNTHESIS-S, (4), 1999, pp. 607-614
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
4
Year of publication
1999
Pages
607 - 614
Database
ISI
SICI code
0039-7881(199904):4<607:AATEPT>2.0.ZU;2-Z
Abstract
Ketones 7 and 8, available from (-)-beta-pinene by Fe-catalyzed CO-insertio n, can be transformed into enantiomerically pure taxoidic A-ring building b locks like 10 or 13 via a concise and novel route. For the subsequent A,B-r ing synthesis, a ring closing metathesis approach is described for the firs t time.