Functionalization by metalation of the benzene moiety of benzodiazines. Determination of structures by long-range H-1-N-15 correlation at natural abundance. Diazines XXV.

Authors
Chapoulaud, VG Salliot, I Ple, N Turck, A Queguiner, G
Citation
Vg. Chapoulaud et al., Functionalization by metalation of the benzene moiety of benzodiazines. Determination of structures by long-range H-1-N-15 correlation at natural abundance. Diazines XXV., TETRAHEDRON, 55(17), 1999, pp. 5389-5404
Citations number
40
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
17
Year of publication
1999
Pages
5389 - 5404
Database
ISI
SICI code
0040-4020(19990423)55:17<5389:FBMOTB>2.0.ZU;2-R
Abstract
The first lithiation of the benzene moiety of various quinazolinones, quino xalines, and phthalazines has been performed. The effects of kind and posit ions of various directing groups towards the regioselectivity of the metala tion have been studied. Unambiguous structure determinations of quinoxaline derivatives have been carried out by applying NMR GHMBC H-1-N-15 sequence. (C) 1999 Elsevier Science Ltd. All rights reserved.