F. Bigi et al., A revision of the Biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF, TETRAHEDR L, 40(17), 1999, pp. 3465-3468
The reaction of aldehydes, beta-dicarbonyl compounds and urea (Bigineili re
action) has been performed over solid acid catalysis, under solventless con
ditions or in water affording dihydropyrimidines in good yield and selectiv
ity. (C) 1999 Elsevier Science Ltd. All rights reserved.