A concise synthesis of unnatural (+)-5-epi-nojirimycin-delta-lactam via asymmetric reduction of a meso-imide

Authors
Kang, JY Lee, CW Lim, GJ Cho, BT
Citation
Jy. Kang et al., A concise synthesis of unnatural (+)-5-epi-nojirimycin-delta-lactam via asymmetric reduction of a meso-imide, TETRAHEDR-A, 10(4), 1999, pp. 657-660
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
4
Year of publication
1999
Pages
657 - 660
Database
ISI
SICI code
0957-4166(19990226)10:4<657:ACSOU(>2.0.ZU;2-A
Abstract
Nojirimycin-delta-lactam skeleton was synthesized by asymmetric reduction o f a cyclic triacetyloxy meso imide with a chiral beta-amino thiol ligand. T he resulting product was converted to unnatural (+)-5-epi-nojirimycin-delta -lactam. (C) 1999 Elsevier Science Ltd. All rights reserved.