Organisms have been producing mineralized skeletons for the past 550 m
illion years. They have evolved many different strategies for improvin
g these materials at almost all hierarchical levels from Angstroms to
millimetres. Key components of biological materials are the macromolec
ules, which are intimately involved in controlling nucleation, growth,
shaping and adapting mechanical properties of the mineral phase to fu
nction. One interesting tendency that we have noted is that organisms
have developed several strategies to produce materials that have more
isotropic properties. Much can still be learned from studying the prin
ciples of structure-function relations of biological materials. Some o
f this information may also provide new ideas for improved design of s
ynthetic materials.