Biochemical alterations of uterine leiomyoma extracellular matrix in type IV Ehlers-Danlos syndrome

Authors
Wegrowski, Y Bellon, G Quereux, C Maquart, FX
Citation
Y. Wegrowski et al., Biochemical alterations of uterine leiomyoma extracellular matrix in type IV Ehlers-Danlos syndrome, AM J OBST G, 180(4), 1999, pp. 1032-1034
Citations number
2
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
ISSN journal
00029378 → ACNP
Volume
180
Issue
4
Year of publication
1999
Pages
1032 - 1034
Database
ISI
SICI code
0002-9378(199904)180:4<1032:BAOULE>2.0.ZU;2-Z
Abstract
Collagens and glycosaminoglycans were assessed in 6 leiomyomas from otherwi se healthy ("control") patients and 1 leiomyoma from a patient with type IV Ehlers-Danlos syndrome. The type IV Ehlers-Danlos leiomyoma contained less type III collagen and dermatan sulfate than control leiomyomas. This might contribute to the formation of a defective collagen network in type IV Ehl ers-Danlos syndrome.