Ke. Sharpless et al., CERTIFICATION OF NUTRIENTS IN STANDARD-REFERENCE-MATERIAL-1846 - INFANT FORMULA, Journal of AOAC International, 80(3), 1997, pp. 611-621
In 1996, the National Institute of Standards and Technology (NIST) rel
eased Standard Reference Material 1846 (Infant Formula), which can be
used as a control material for assigning values to in-house control ma
terials and for validating analytical methods for measurement of proxi
mates, vitamins, and minerals in infant formula and similar matrixes.
The SRM was manufactured by preparing a spray-dried formula base conta
ining fat, protein, carbohydrates, and minerals and then combining tha
t formula base with a dry-blend vitamin premix that supplied the vitam
ins. The Certificate of Analysis for SRM 1846 provides assigned values
for concentrations of proximates (fat, protein, etc.), vitamins, and
minerals for which product labeling is required by the Infant Formula
Act of 1980 and by the Nutrition Labeling and Education Act of 1990. T
hese assigned values were based on agreement of measurements by NIST a
nd/or collaborating laboratories. Certified values are provided for vi
tamins A (trans), E, C, B-2, and B-6 and niacin. Noncertified values a
re provided for solids, ash, fat, nitrogen, protein, carbohydrate, cal
ories, vitamin D, delta-tocopherol, gamma-tocopherol, Vitamin B-1, vit
amin B-12, folic acid, pantothenic acid, biotin, choline, inositol, ca
lcium, phosphorus, magnesium, iron, zinc, copper, sodium, potassium, a
nd chloride. Information values are provided for iodine, manganese, se
lenium, and vitamin K.