End-column amperometric detection of 5-fluorouracil by capillary zone electrophoresis with a carbon fiber microelectrode

Authors
You, TY Wang, XQ Yang, XR Wang, EK
Citation
Ty. You et al., End-column amperometric detection of 5-fluorouracil by capillary zone electrophoresis with a carbon fiber microelectrode, ANAL LETTER, 32(6), 1999, pp. 1109-1119
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL LETTERS
ISSN journal
00032719 → ACNP
Volume
32
Issue
6
Year of publication
1999
Pages
1109 - 1119
Database
ISI
SICI code
0003-2719(1999)32:6<1109:EADO5B>2.0.ZU;2-D
Abstract
A rapid and sensitive detection method for the determination of 5-fluoroura cil(5-FU) in real samples such as human urine and bovine serum albumin (BSA ) was described. A carbon fiber microdisk electrode was used to perform end -column amperometric detection in capillary zone electrophoresis. The detec tion limit was as low as 2.5x10(-7) M and the wider linear range for the co ncentration was between 5x10(-6) and 1x10(-4) M with a correlation coeffici ent of 0.995.