Analytical resolution of 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones using a cellulose chiral stationary phase

Authors
Sarac, S Yarym, M Ertan, M
Citation
S. Sarac et al., Analytical resolution of 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones using a cellulose chiral stationary phase, ANAL LETTER, 32(6), 1999, pp. 1245-1254
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL LETTERS
ISSN journal
00032719 → ACNP
Volume
32
Issue
6
Year of publication
1999
Pages
1245 - 1254
Database
ISI
SICI code
0003-2719(1999)32:6<1245:ARO4>2.0.ZU;2-7
Abstract
Racemic 4-aryl-1,2,3,4,5,6,7, 8-octahydroquinazoline-2-thiones were resolve d into their enantiomers by HPLC on cellulose tris(4-methylbenzoate) coated on silica gel using ethanol:n-hexane (70:30) as a mobile phase. A convenie nt method for preparation of cellulose tris(4-methylbenzoate) chiral statio nary phase was described and the enantiomers were characterized by some chr omatographic data.