Role of red blood cells in pharmacokinetics of chemotherapeutic agents

Authors
Schrijvers, D Highley, R De Bruyn, E Van Oosterom, AT Vermorken, JB
Citation
D. Schrijvers et al., Role of red blood cells in pharmacokinetics of chemotherapeutic agents, ANTI-CANC D, 10(2), 1999, pp. 147-153
Citations number
33
Categorie Soggetti
Pharmacology,"Onconogenesis & Cancer Research
Journal title
ANTI-CANCER DRUGS
ISSN journal
09594973 → ACNP
Volume
10
Issue
2
Year of publication
1999
Pages
147 - 153
Database
ISI
SICI code
0959-4973(199902)10:2<147:RORBCI>2.0.ZU;2-B
Abstract
After oral or parenteral administration of chemotherapeutic agents, these d rugs are transported to the tissues by the blood in different fractions: pl asma water, plasma proteins or cells. In this review, the role of the red b lood cell in storage, transport and metabolism of different anti-cancer dru gs is described. [(C) 1999 Lippincott Williams & Wilkins.].