Up to 25% of hospitalized patients undergo urinary catheterization, and abo
ut 5% develop bacteriuria each day of catheterization, Catheter-related bac
teriuria is associated with increased morbidity and mortality. We performed
an evidence-based synthesis of the literature on preventing catheter-assoc
iated urinary tract infections (UTIs) to develop recommendations for clinic
ians. Catheterization should be avoided when not required and when needed,
should be terminated as soon as possible. Use of suprapubic and condom cath
eters may be associated with a lower risk of UTI than use of urethral cathe
ters, Aseptic catheter insertion and a properly maintained closed drainage
system are crucial to reducing the risk of bacteriuria, Instillation of ant
imicrobial agents into the bladder or urinary drainage bag and rigorous mea
tal cleansing seem to be of little benefit. Use of urinary catheters coated
with silver alloy may reduce the risk of UTI, Systemic antimicrobial drug
therapy seems to prevent UTIs, but primarily for patients catheterized for
3 to 14 days. Antibiotic drug prophylaxis is especially valuable in patient
s undergoing transurethral resection of the prostate or renal transplantati
on. Using these methods, urinary catheter-associated UTI can often be preve
nted for weeks, but not longer terms.