SYNTHESIS OF VINCA ALKALOIDS AND RELATED-COMPOUNDS .74. REACTION OF (+ 4,6,7,12,12-BETA-OCTAHYDROINDOLO[2,3-A]QUINOLIZINE WITH HYDRIDE AND N-NUCLEOPHILES/
G. Kalaus et al., SYNTHESIS OF VINCA ALKALOIDS AND RELATED-COMPOUNDS .74. REACTION OF (+ 4,6,7,12,12-BETA-OCTAHYDROINDOLO[2,3-A]QUINOLIZINE WITH HYDRIDE AND N-NUCLEOPHILES/, Journal of chemical research. Synopses, (10), 1995, pp. 382
Reaction of the title methanesulfonate ester 1b with sodium azide gave
derivatives 4 and 5 and with lithium tetrahydroaluminate the dialkyl
compound 7, while with primary amines, in addition to the expected pro
ducts (8a-r), compounds 9k-m possessing an unexpected ring system are
obtained.