A. Hiller et al., Transient neurological symptoms after spinal anaesthesia with hyperbaric 5% lidocaine or general anaesthesia, BR J ANAEST, 82(4), 1999, pp. 575-579
Citations number
20
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Transient neurotoxicity of concentrated local anaesthetics has been thought
to be the main reason for transient neurological symptoms after spinal ana
esthesia. Profound musculoligamental relaxation by high doses of local anae
sthetics may contribute to the development of postoperative musculoskeletal
pain. In order to evaluate the role of the loss of strength of the support
ive structures of the spine in the development of transient neurological sy
mptoms, 60 patients (ASA I-II) undergoing minor orthopaedic, varicose vein
or inguinal hernia operations were allocated randomly to receive spinal ana
esthesia with hyperbaric lidocaine 50 mg ml(-1) (85-100 mg) or balanced gen
eral anaesthesia with neuromuscular block. Patients were interviewed 24 h l
ater and after 1 week they returned a written questionnaire. Transient neur
ological symptoms, consisting of pain in the buttocks or pain radiating sym
metrically to the lower extremities, occurred in eight patients (27%) recei
ving spinal anaesthesia and in one patient (3%) receiving general anaesthes
ia (P<0.05). We conclude that a transient neurotoxic effect of hyperbaric l
idocaine 50 mg ml(-1) is probably the main reason for transient neurologica
l symptoms after spinal anaesthesia but musculoligamental relaxation may co
ntribute to the development of low back or leg pain after both anaesthetic
techniques.