alpha-Halogenohydrazides: useful starting material for the synthesis of hydrazinoazapeptides and azauracils

Authors
Barre, C Carret, S Guerro, M Le Grel, P Baudy-Floc'h, M
Citation
C. Barre et al., alpha-Halogenohydrazides: useful starting material for the synthesis of hydrazinoazapeptides and azauracils, CAN J CHEM, 77(2), 1999, pp. 263-270
Citations number
20
Categorie Soggetti
Chemistry
Journal title
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
ISSN journal
00084042 → ACNP
Volume
77
Issue
2
Year of publication
1999
Pages
263 - 270
Database
ISI
SICI code
0008-4042(199902)77:2<263:AUSMFT>2.0.ZU;2-3
Abstract
An efficient method for the synthesis of pseudodipeptides, which combines a n aza glycine residue with various hydrazinoacid moieties by simple substit ution of the halogen of alpha-halohydrazides, is described, Some of these h ydrazinoazapeptides lead to hydrazones by oxidation or to azaaminouracils b y cyclization.