The reactivity of 3-methyl-cis-2,6-diphenyl-4-piperidone 1 has been explore
d to develop a variety of heterocyclic compounds viz., diazepinone 3, oxaze
pinone 4, thiadiazole 8, gamma-carboline 13, isoxazolyl and pyrazolyl tetra
hydropyridines 16 and 17 and various spiro heterocycles 18,19 and 21 by the
functionalization of carbonyl and active methylene centres.