Extending the concept of isochrons from oscillatory to excitable systems for modeling an excitable neuron

Citation
N. Ichinose et al., Extending the concept of isochrons from oscillatory to excitable systems for modeling an excitable neuron, INT J B CH, 8(12), 1998, pp. 2375-2385
Citations number
21
Categorie Soggetti
Multidisciplinary
Journal title
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS
ISSN journal
02181274 → ACNP
Volume
8
Issue
12
Year of publication
1998
Pages
2375 - 2385
Database
ISI
SICI code
0218-1274(199812)8:12<2375:ETCOIF>2.0.ZU;2-9
Abstract
In this paper, we study an excitable and nonoscillating neuron on the basis of a technique of extending the concept of isochrons from oscillatory to e xcitable systems. The extended isochrons allow reduction of an excitable sy stem described by possibly high dimensional differential equations to a sim pler system. We analytically derive a one-dimensional model of an excitable neuron stimulated by instantaneous pulses with the technique of the extend ed isochrons and show its similarity to an isochronal map numerically obtai ned from the FitzHugh-Nagumo model. Response characteristics of the one-dim ensional model to periodic impulsive stimulations are also analyzed numeric ally.