K. Horio et al., Effect of temporary hepatic venous occlusion on hepatic arterial embolization - An experimental study, INV RADIOL, 34(5), 1999, pp. 341-347
Citations number
19
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
RATIONALE AND OBJECTIVES. The authors evaluated the effect of hepatic venou
s occlusion on hepatic arterial embolization in rats,
METHODS. A Lipiodol-Iopamidol mixture was injected into the proper hepatic
artery in rats during clamping the right side of the hepatic venous conflue
nce. The distribution of Lipiodol-Iopamidol mixture in the sinusoids was an
alyzed by histological examination with en bloc silver impregnation. The ex
tent of the distribution of Lipiodol-Iopamidol mixture was compared in sinu
soids with hepatic venous occlusion and in sinusoids without hepatic venous
occlusion,
RESULTS. Lipiodol-Iopamidol mixture was more widely distributed in the lobu
les with hepatic venous occlusion than in the lobules without occlusion,
CONCLUSIONS. Hepatic venous occlusion may enhance the effect of hepatic art
erial embolization using Lipiodol emulsions and could be useful in the trea
tment of hepatocellular carcinoma.