Microorganisms of the genus Abiotrophia, members of the oral flora, are kno
wn as important causes of bacterial endocarditis. In this study, we report
two individual cases of acute vitreous infection caused by Abiotrophia adia
cens and Abiotrophia defectiva approximately a week after cataract extracti
on. Abiotrophia isolates were recovered by cultivation of vitreous humor on
chocolate agar and identified via conventional and API 20 Strep identifica
tion systems. An 83-year-old male patient (A) and an 80-year old female pat
ient (B) demonstrated almost identical symptoms of infectious endophthalmit
is manifested as hypopyon and opaque media. The vision of both patients was
reduced to detection of hand motion in the left and the right eyes, respec
tively. An emergency pars plana core vitrectomy was performed, and intraocu
lar antibiotics were administered to each patient, who presented 8 months a
part in two different institutions. Patients A and B Here treated with an i
ntravitreal injection of vancomycin-amikacin and vancomycin ceftazidime, re
spectively, which resulted in complete recovery.