Invasive aspergillosis caused by Aspergillus ustus: Case report and review

A case of invasive pulmonary aspergillosis in an allogeneic bone marrow tra nsplant recipient caused by Aspergillus ustus is presented. A. ustus was al so recovered from the hospital environment, which may indicate that the inf ection Has nosocomially acquired. A literature review revealed seven cases of invasive infections caused by A. ustus, and three of these were primaril y cutaneous infections. In vitro susceptibility testing of 12 A. ustus isol ates showed that amphotericin B and terbinafine had fungicidal activity and that itraconazole and voriconazole had fungistatic activity.