Localization study of Co-phthalocyanines in cells by Raman micro(spectro)scopy

Authors
Arzhantsev, SY Chikishev, AY Koroteev, NI Greve, J Otto, C Sijtsema, NM
Citation
Sy. Arzhantsev et al., Localization study of Co-phthalocyanines in cells by Raman micro(spectro)scopy, J RAMAN SP, 30(3), 1999, pp. 205-208
Citations number
11
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF RAMAN SPECTROSCOPY
ISSN journal
03770486 → ACNP
Volume
30
Issue
3
Year of publication
1999
Pages
205 - 208
Database
ISI
SICI code
0377-0486(199903)30:3<205:LSOCIC>2.0.ZU;2-G
Abstract
An investigation of intracellular localization of Co-phthalocyanines is rep orted. The Raman images of K562 cells stained with phthalocyanine were acqu ired. To understand the peculiarities of the Raman images, measurements wer e performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out usi ng the fluorescence probes FITC-dextran and acridine orange by means of Ram an and fluorescence microscopy, Partial colocalization with both probes was revealed, Copyright (C) 1999 John Wiley & Sons, Ltd.