New sesquiterpenes from a Taiwanese marine sponge of the genus Parahigginsia

Authors
Shen, YC Chen, CY Duh, CY
Citation
Yc. Shen et al., New sesquiterpenes from a Taiwanese marine sponge of the genus Parahigginsia, J CHIN CHEM, 46(2), 1999, pp. 201-204
Citations number
9
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
ISSN journal
00094536 → ACNP
Volume
46
Issue
2
Year of publication
1999
Pages
201 - 204
Database
ISI
SICI code
0009-4536(199904)46:2<201:NSFATM>2.0.ZU;2-U
Abstract
An undescribed Taiwanese marine sponge of the genus Parahigginsia yielded t wo new sesquiterpene hydrocarbons-parahigginine (1) and parahigginone (2). The structures of the new compounds were established on the basis of NMR sp ectroscopic and mass spectrometric data. Compounds 1 and 2 exhibited modera te cytotoxicity against murine P-388 and human KB-16, A-549, and HT-29 tumo r cells.