Characterization and conformational studies of a novel trinitro steroid using 2D-NMR

Authors
Katoch, R Sridharan, R Trivedi, GK
Citation
R. Katoch et al., Characterization and conformational studies of a novel trinitro steroid using 2D-NMR, J INDIAN CH, 75(10-12), 1998, pp. 543-547
Citations number
19
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
ISSN journal
00194522 → ACNP
Volume
75
Issue
10-12
Year of publication
1998
Pages
543 - 547
Database
ISI
SICI code
0019-4522(199810/12)75:10-12<543:CACSOA>2.0.ZU;2-P
Abstract
Conformational analysis of nitro substituted 4-en-3-one steroids has been f urther investigated using high resolution 2D-NMR techniques. An attempt on the preparation of 6 beta-nitrocholest-4-en-3-one resulted in a new trinitr o steroid, 2,2,6 beta-trinitrocholest-4-en-3-one. These compounds have been characterized using COSY, HETCOR, NOESY experiments and the probable pathw ays to these products have been discussed.