New advances in understanding the molecular biology of plant/potyvirus interactions

In recent years, researchers have adopted many new technologies to help und erstand potyvirus pathogenesis. Their findings have illuminated key aspects of the interactions between the host and the virus, and between the virus and its aphid vector. This review focuses on advances in our understanding of the molecular determinants of systemic infection, symptom expression, ap hid and seed transmission, and natural and engineered resistance to potyvir uses. Very recent developments in the area of post-transcriptional gene sil encing indicate not only that the process is fundamental to engineered resi stance, but may also underlie many aspects of the biology of plant viruses.